Tuesday, January 31, 2012

Allen West to national Dems: ???Get the hell out of the United States of America??? (Daily Caller)

Rep. Allen West did not mince words on Sunday, telling national Democrats to get out of Florida and, for that matter, out of the country.

In a speech at the Lincoln Day Dinner where Herman Cain endorsed former Speaker of the House Newt Gingrich, the Palm Beach Post reports that West drew the greatest applause with his fiery speech.

?We need to let President Obama, Harry Reid, Nancy Pelosi and my dear friend the chairman of the Democratic National Committee [Debbie Wasserman Schultz], let them know Florida ain?t on the table.?

Schultz has spent the last number of weeks stalking the Republican primaries, seeking media appearances in Iowa, New Hampshire, South Carolina and, now, Florida, with efforts to garner media attention and knock GOP candidates off balance.

?Take your message of economic dependency, take your message of enslaving the entrepreneurial will and spirit of the American people somewhere else,? West continued. ?You can take it to Europe, you can take it to the bottom of the sea, you can take it to the North Pole, but get the hell out of the United States of America.?

?This is not about 1 percent or 99 percent ? this is about 100 percent. This is about 100 percent of America, and I will not stand back and watch anyone defame, degrade or destroy that which my father fought for, my older brother, my father-in-law, my nephew and all my friends in uniform,? West concluded. ?I will not allow President Obama to take the United States of America and destroy it.?

?If that means I?m the number one target for the Democratic party, all I have to say is one thing: Bring it on.?

West is indeed a high-value target for Democrats. The Republican freshman and tea party favorite?s district has been redrawn since he won election, and the new district is more favorable to Democrats.

Join the conversation on The Daily Caller

Read more stories from The Daily Caller

Allen West to national Dems: 'Get the hell out of the United States of America'

Laura Ingraham: 'Tea party doesn?t have the great strength that the old media believe' [VIDEO]

Global warming activists seek to purge 'deniers' among local weathermen

College to offer class on Beyonce

It's starting to look like maybe Occupiers really are kind of violent and stuff?

Source: http://us.rd.yahoo.com/dailynews/rss/democrats/*http%3A//news.yahoo.com/s/dailycaller/20120130/pl_dailycaller/allenwesttonationaldemsgetthehelloutoftheunitedstatesofamerica

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Most banks tightening credit to Europe, Fed says (Reuters)

WASHINGTON (Reuters) ? More than two-thirds of banks in a Federal Reserve survey of senior loan officers said they had tightened credit to European financial firms in January, underscoring the continent's severe banking crisis.

The survey, published on Monday, also found U.S. banks snapping up business from their beleaguered European competitors, countering the notion that new regulations are hurting Wall Street's competitiveness.

"About half of the respondents who reported competing with European banks noted such an increase in business," the Fed said.

There was also "more widespread tightening of standards" to non-financial firms that have U.S. operations and significant exposure to European economies.

Policymakers worry that a freezing up of bank lending in Europe could spill over into the United States, potentially threatening a fragile economic recovery.

Still, the findings painted a more benign picture of U.S. credit markets: Domestic lending standards were largely unchanged this month and loan demand picked up somewhat.

"The uptick in credit demand is a welcome development for the recovery as it could be an indication that businesses and consumers alike are beginning to feel more confident," said Millan Mulraine, a strategist at TD Securities in Toronto.

Demand for home equity loans fell, the survey found, a sign of the housing sector's persistent weakness.

(Reporting By Pedro Nicolaci da Costa; Editing by Neil Stempleman, Andrew Hay and Dan Grebler)

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/nm/20120130/bs_nm/us_usa_fed_europe

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Monday, January 30, 2012

How to tame the super PACs (CNN)

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SAG Awards menu is months in the making

In this Oct. 19, 2011 photo, SAG Awards producer Kathy Connell, left, and SAG Awards supervising producer Mick McCullough participate in the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

In this Oct. 19, 2011 photo, SAG Awards producer Kathy Connell, left, and SAG Awards supervising producer Mick McCullough participate in the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

In this Oct. 19, 2011 photo, a plate of chopped chicken salad with apples, radicchio, walnuts and whole grain mustard sits on display during the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

In this Oct. 19, 2011 photo, from left, SAG Awards Committee Chair JoBeth Williams, SAG Awards Committee member Paul Napier, chef Suzanne Goin, of Lucques Catering, and SAG Awards event designer Keith Greco take part during the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

In this Oct. 19, 2011 photo, a plate with grilled chicken breast with black rice, pea shoots and tangerine vinaigrette displays during the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

In this Oct. 19, 2011 photo, a bottle of champagne sits on display during the SAG Awards tasting and table decor preview at Lucques restaurant in Los Angeles. The SAG Awards will be held Sunday, Jan. 29, 2012. (AP Photo/Matt Sayles)

(AP) ? When your dinner party guests include Brad Pitt, George Clooney, Kate Winslet and Glenn Close, and the whole affair is televised live, it can take months to plan the menu. That's why the team behind the Screen Actors Guild Awards began putting together the plate for Sunday's ceremony months ago.

It was still summer when show producer Kathy Connell and executive producer and director Jeff Margolis first sat down with chef Suzanne Goins of Los Angeles eatery Lucques with a tall order: Create a meal that is delicious at room temperature, looks beautiful on TV, is easy to eat and appeals to Hollywood tastes. Oh, and no poppy seeds, soups, spicy dishes, or piles of onions or garlic.

"It can't drip, stick in their teeth or be too heavy," Connell said. "We have to appease all palates."

The chef put together a plate of possibilities: Slow-roasted salmon with yellow beets, lamb with cous cous and spiced cauliflower and roasted root vegetables with quinoa. There was also a chopped chicken salad and another chicken dish with black beans.

To ensure the dishes are both tasty and TV-ready, Connell and Margolis, along with the SAG Awards Committee and the show's florist and art director, dined together at this summertime lunch on tables set to replicate those that will be in the Shrine Exposition Center during the ceremony. The pewter, crushed-silk tablecloths and white lilies you'll see on TV Sunday were also chosen months ago.

The diners discussed the look of the plate, the size of the portions and the vegetarian possibilities.

"We'd like the portions a little larger," Connell told the chef.

"And a little more sauce on the salmon," Margolis added.

Come Sunday, it's up to Goins to prepare 1,200 of the long-planned meals for the A-list audience.

___

Online:

www.sagawards.org

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-01-28-SAG%20Awards-Menu/id-c4447ed94e484ab19d8a5d1836eb2f5c

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Sunday, January 29, 2012

Scientists reveal how cholera bacterium gains a foothold in the gut

Saturday, January 28, 2012

A team of biologists at the University of York has made an important advance in our understanding of the way cholera attacks the body. The discovery could help scientists target treatments for the globally significant intestinal disease which kills more than 100,000 people every year.

The disease is caused by the bacterium Vibrio cholerae, which is able to colonise the intestine usually after consumption of contaminated water or food. Once infection is established, the bacterium secretes a toxin that causes watery diarrhoea and ultimately death if not treated rapidly. Colonisation of the intestine is difficult for incoming bacteria as they have to be highly competitive to gain a foothold among the trillions of other bacteria already in situ.

Scientists at York, led by Dr. Gavin Thomas in the University's Department of Biology, have investigated one of the important routes that V. cholerae uses to gain this foothold. To be able to grow in the intestine the bacterium harvests and then eats a sugar, called sialic acid, that is present on the surface of our gut cells.

Collaborators of the York group at the University of Delaware, USA, led by Professor Fidelma Boyd, had shown previously that eating sialic acid was important for the survival of V. cholerae in animal models, but the mechanism by which the bacteria recognise and take up the sialic was unknown.

The York research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), demonstrates that the pathogen uses a particular kind of transporter called a TRAP transporter to recognise sialic acid and take it up into the cell. The transporter has particular properties that are suited to scavenging the small amount of available sialic acid. The research also provided some important basic information about how TRAP transporters work in general.

The leader of the research in York, Dr. Gavin Thomas, said: "This work continues our discoveries of how bacteria that grow in our body exploit sialic acid for their survival and help us to take forward our efforts to design chemicals to inhibit these processes in different bacterial pathogens."

The research is published in the latest issue of the Journal of Biological Chemistry and was primarily the work of Dr Christopher Mulligan, a postdoctoral fellow in the Dr Thomas's laboratory.

###

University of York: http://www.york.ac.uk

Thanks to University of York for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/117153/Scientists_reveal_how_cholera_bacterium_gains_a_foothold_in_the_gut

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Botched Drug Raid or Botched Drug Robbery? (Theagitator)

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Saturday, January 28, 2012

England looks to US sports to add glitz to FA Cup

By ROB HARRIS

updated 7:56 p.m. ET Jan. 26, 2012

LONDON - Seeking to restore the allure of the FA Cup, English soccer is looking to American sports to see how some glitz can be added to the final of world soccer's oldest domestic cup competition.

Once the main event in the English soccer calendar and a must-see TV event globally, some of the cup's appeal has been lost as the more lucrative Premier League and Champions League appear to be outshining the 140-year competition.

Wembley Stadium has staged NFL regular-season games for five years, giving a glimpse of how the FA Cup final could be spiced up with more entertainment and glamor there.

"We are always learning, we are investing more internal marketing resources alongside that (broadcaster) ITV and Budweiser put in," FA General Secretary Alex Horne said while overlooking the Wembley field.

"As a collective we all think we can make something more of the day of the final and the event ? whether it's on the pitch or the buildup to the event.

"Of course we can learn from the NBA events or the NFL events ... there are many people who do this well."

While looking west across the Atlantic for inspiration on event management, Horne is not losing sight of the competition's big fan base in the East.

"The FA Cup continues to attract huge audiences throughout the world, especially in Asia," Horne said. "China and Thailand are huge markets for English football and the FA Cup in particular. We had a global audience of half a billion for the FA Cup final last year, so we know it's a very relevant product."

But the FA Cup final could be moved from its traditional kickoff time this season in a bid to boost British TV audiences, potentially hitting Asian viewing figures.

The final is set to be at 5:15 p.m. instead of 3 p.m, while talks are under way with the Premier League about preventing a repeat of last season when the match had to be played on the same day as a topflight league program for the first time in 50 years.

That led to Manchester United clinching a record 19th league title just before local rival City ended a 35-year trophy drought by lifting the FA Cup at Wembley.

"The important thing for us is giving (the final) an identity, even if it is not on the last day of the season," Horne said.

The problem of the FA Cup final sharing the day with other big matches in England could be exacerbated by the Champions League final returning to Wembley in 2013 after being staged there last May. UEFA needs the stadium for two weeks before the match.

But ahead of the fourth round this weekend, the FA has sought to highlight the enduring value of the cup, with a study showing that clubs have collectively earned around $1 billion over the past 10 years in prize money, TV payments and ticket revenue.

Such rewards can have a transformational effect on teams ? particularly those lower down the pecking order.

"When Burton secured a replay at Old Trafford (against Manchester United in 2006) they earned $1.1 million in that year," Horne said. "That enabled them to pay off the debt on their stadium, invest in playing talent and ultimately progress into the Football League.

"Crawley last year earned $2.4 million from the competition, including a 1-million pound ($1.6 million) payday at Old Trafford."

The FA Cup is in the first year of a $38 million, three-year title sponsorship deal with American beer brand Budweiser.

___

Rob Harris can be reached at http://twitter.com/RobHarrisUK

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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US women qualify for Olympics

The U.S. women's soccer team booked their way to London on Friday night with a 3-0 victory over Costa Rica in the semifinals of the CONCACAF qualifying tournament.

Yankee matchup

With the two biggest stars on the U.S. national team facing each other for the first time in 6 years, Landon Donovan?leads Everton past Clint Dempsey's Fulham.

Source: http://nbcsports.msnbc.com/id/46156468/ns/sports-soccer/

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SGP iPhone 4 / 4S Leather Wallet Case Valentinus Series Review

My iPhone 4 is always in a bumper case, and I carry it inside my Dooney and Bourke Multi-Function Zip Around wallet.? That wallet is small enough to fit in my purse, but it holds some cards and cash, so I can just grab it and go.? If you’d like an even smaller wallet plus [...]

Source: http://the-gadgeteer.com/2012/01/26/sgp-iphone-4-4s-leather-wallet-case-valentinus-series-review/

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Friday, January 27, 2012

Napoleon Perdis: Desert Chic

I've been living the desert dream lately, channeling my alter ego of a 'desert rat' in Palm Springs where I am lucky enough to have a home. That soul-stirring expanse of sky and day-long stretches of winter sun topped off by the cool mountain air in the evenings really helps me to reset and reframe after a crazy week in my Hollywood office. The snowbirds are in town right now, jetting into Palm Springs airport from San Francisco, Chicago, Minneapolis and Toronto to escape a harsher winter. And it only adds to the people-watching potential that I love about this part of the world. I've been starting most days with breakfast at Jake's or Cheeky's and then taking a drive along Palm Canyon, scouting around for collectables at the estate sales and my favorite furniture and design stores. A friend of mine calls it 'trinketeering' and it's one of my favorite ways to spend the weekend. When I'm in town I never miss a morning at Misty's Consignment store (www.mistysconsignments.com). Owner Misty Davis has amazing connections, especially within the Old Movie Colony, and receives daily deliveries of vintage jewelry, impeccable mid-century furniture, and great art. I hate the thought that I could be missing out on a must-have piece if I don't get there!

But it's not just about what's in store but who's in store. I've been clocking some incredibly chic women on their own trinketeering excursions, working their resort wear and a refreshingly low-key look. But let's not confuse low key with low fi; these women are still glamazons which means there's great grooming and diligent maintenance going on but they're far more covert about it. Complexions can only be described as perfection: clear, refined, with an almost imperceptible wash of dewy base. [Watch this space: sheer, dewy tints of hydrating foundation and tinted moisturizers are making a comeback!] Eyelashes are artfully extended by way of mascara or super subtle lash extensions while cheeks are very carefully contoured - no obvious flush of blush! Gravity isn't really on anyone's side let's face it, but these Palm Springs princesses have found a way to coax it into submission and it's all subtle sculpting and soft, skin-like shades that enhance your natural features. I'm definitely tuning into a strong nude makeup vibe edging its way back into makeup bags and onto the streets and it has inspired me to put color to one side and explore the face-shaping, eye-opening capabilities of a more neutral, nude palette for next season. 2012 is all about skinspiration!

?

Follow Napoleon Perdis on Twitter: www.twitter.com/NapoleonPerdis

Source: http://www.huffingtonpost.com/napoleon-perdis/desert-chic_b_1236828.html

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Thursday, January 26, 2012

Video: Florida remains up-for-grabs



>>> the republican presidential candidates have been bashing president obama 's address while they're on the road in florida today . larry kudlow interviewed mitt romney for his show tonight. romney told him that many obama's millionaire's tax is aimed directly at him. while newt gingrich told the "today" show he liked obama's rhetoric, but that was it.

>> well, it's designed to commit me if i'm the nominee, if i happen to be not the nominee, he's trying to divide america and try and say that republicans are all about the rich people . look, republicans are about fighting to help middle class americans get better jobs.

>> i find the gap between president obama 's words and his deeds to be sort of astounding. you know, he ran on bringing us together. he ran on yes, we can. yet, last night he seemed to be setting up an entire year of divisiveness.

>> meanwhile, some new poll numbers out today showed newt gingrich taking the lead in the sunshine state . the quinnipiac poll talked to voters before and after the south carolina primary , before the primary, romney was polling at about 37%, gingrich in second at 26%. but after the south carolina primary , take a look at this now. gingrich soars to 40%. but the race cos still be anyone's. 3% say they still might change their minds. want to bring in the "news nation" political panel. michael smerconish is a radio talk show host, also an msnbc contributor as well, a.b. stoddard, columnist for the hill. good afternoon to both of you.

>> hi, craig .

>> michael , let's start with you. newt gingrich wiping out a 12-point lead by mitt romney in florida . he did the same thing in south carolina . his momentum now giving him more momentum. how likely at this point that romney loses florida , and what will that mean for the race going forward?

>> i think this would be the contest that would wipe the slate clean because up till now, folks have been saying romney is still the proverbial front-runner but if he should lose florida , a far more diverse state than was south carolina in terms of those who come out and comprise the primary electorate, this would be a very significant setback. you know, craig , here's the state of the union address last night. i'm convinced mitt romney made the decision to release his tax returns yesterday, thinking he would get buried in all the coverage of the state of the union . and instead, it seems to have played directly into the hand of the president who was prepared already to talk about income disparity and here now is the romney tax return , which just furthered the narrative the white house is trying to create of him.

>> a.b., it did sound at times last night that the president was speaking as if mitt romney was going to be 9 nominee. a lot of the themes highlighted last night were the themes that would lend themselves to mitt romney .

>> they are. and michael 's right that the release of the tax returns showing that a man with no job is earning almost $60,000 a day in income off his investments from years gone by is really quite a stark example with most americans. but i think that president obama is going to run on the same themes no matter who is the nominee. he's decided he's not going to run on the situation with the economy which he says is better but he's not going to run on 8% unemployment. he's not going to run on health care reform law. he's going to run on the fact that things could be worse and the fact that there are these differences between republican economic positions which he says destroy the middle class and his proposal to defend the middle class , which he says you know, is having this make or break moment. it doesn't matter. even if newt gingrich becomes the republican nominee, you'll hear the same thing from president obama this summer and fall.

>> i want to come back to the state of the union in a moment. i want to make sure we get to what happened in florida today . newt gingrich spending part of the morning on a univision candidate forum in miami trying to court hispanic voters. a huge continuigency in the sunshine state . take a listen to what he said this morning. i want to talk about it on the other side.

>> you said that spanish is the language of the living -- of living in a ghetto.

>> it wasn't about spanish. i said about all languages. i am for english as a communionfying language. the fact is you will have a higher income, have greater job opportunities, and have a likelihood of your family having a better future if you're conversant in english.

>> michael , is there a republican candidate that has an advantage over the other with those crucial little important hispanic voters in florida ?

>> well, really interesting, craig , because you know, newt gingrich in commenting about the path towards citizenship as he saw it for the 11 million here already illegally, alienated some elements of thatting and glow base within the gop. the message he offered a few weeks agoing that drew criticism should be one that would earn him fans among hispanics in florida in particular. whether that turns out to be the case, we're about to find out.

>> one of the things that struck me going back to the state of the union last night, a.b., one of the things that struck me was it appeared as if the president was racing for the middle. it looked like and sounded like triangulation all over again. he spent time last night talking about cyberwarfare, talked about fighting mercury poisoning and spent a fair amount of time talking about personal responsibility, as well, themes that you generally don't hear a lot of left leaning politicians talk about a great deal. a.b., is the president going to be able to make that pivot successfully to go from fiery liberal populist to the centrist in the.

>> i think it's going to be tough. last night except for his discussion of economic disparity and tax fairness, i think he was largely a speech to please the base and consolidate the base. in the months to come when there is a general election that has begun in ernest and this is a republican nominee, he's going to bepy videotaping back perhaps on energy and other issues. right now he's talking about expiring the bush tax cuts for the wealthy and fighting for the middle class . republicans are not in agreement with those policies right now.

>> a.b., michael , always a pleasure. thank you both.

Source: http://video.msnbc.msn.com/newsnation/46135961/

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Video: GOP claims Obama?s trying to divide the nation



>>> president obama had some harsh words for congress during his state of the union address last night while he promised -- he promised to power through any republican efforts to block progress on the hill.

>> as long as i'm president, i will working with anyone in this chamber to build on this momentum. but i intend to fight obstruction with action. and i will oppose any effort to the return to the very same policies that brought on this economic crisis in the first place.

>> president obama because he was helping --

>> republicans argue back that the president is talking the talk, but not walking the walk. joining me now is republican congresswoman nan hayworth of new york. congresswoman, good afternoon to you.

>> hi, craig .

>> what do you make of the president's speech last night?

>> well, the president expressed some inspiring ideas and thoughts that we share. these are the broad principles to have every citizen in the united states have a fair opportunity to thrive and to have the dignity of work and to be able to participate in our communities. we all support that. and i do want to emphasize that in the house of representatives , republicans and democrats have been working together.

>> really, congresswoman?

>> really, craig . we've sent 30 bills to the senate.

>> you realize that's not the perception in this country.

>> well, i do. and i'm doing all i can to counter it because the news does need to get out. we have with republican and democratic votes sent 30 bills to the senate. 30. 27 of them have not gone any further.

>> but what about all of those bills and all of the gridlock that we have all watched play out, sometimes for weeks on end whether it's the debt ceiling debate, whether it's the payroll tax cut discussion, as well? what about all of those those big things that you guys haven't gotten done?

>> you know, craig , i am on the conference committee working with colleagues again across the aisle and from the senate to make sure that we get the kind of payroll tax cut extension that republicans and democrats all support. and the issue, as you know, becomes how do we responsibly manage these great goals. that's what this contest throughout the year, if you will, has been about. how do we get consensus on moving forward? and president obama plays a leadership role in that, as well. on the house republican side , it's very true. we have emphasized that we have to think about the next generation and the generations beyond. we're borrowing 40 cents as of this moment, 40 to 41 cents of every dollar the federal government spends. that's all going to be put on the backs of our younger generations. it's not fair to them.

>> i want to specifically about the payroll tax cut. i want to follow up on that because the president called on congress last night to extend it. there was a great deal of applause from both sides i noted. especially from majority leader kantor. is this the something that you can say right now definitively will happen in the next two months? will we see a permanent extension of the payroll tax cut.

>> i'm speaking only for myself, craig , but i believe that is the will of the conference committee and the will of the house of representatives of which i'm a member to extend that payroll tax relief. we have to bear in mind when we do that, we still have to fund the social security trust fund . it's not like taking funds from the general revenues which we want to lower taxes for everybody. but we do have to fund that social security trust fund because those payroll tax contributions go directly to that. and those social security benefits will be paid out eventually. so we have to have the compensatory offsets from other parts of the federal budget . but weigh have lots of opportunity to do that, and i do think that there is a strong will to get that done.

>> last tight, congresswoman, the president called on millionaires in this country and he was slightly more specific than he has been in the past but he basically said if you make more than a million bucks, you should have a tax rate of at least 30%. is that something you could sign off on as well?

>> craig , the other big element that we need so desperate lit is growth. we need jobs. and we're not going to get nearly the growth that we need.

>> yes or no on the 30% rate.

>> the no on a 30% rate, craig . no on a rate hike. let's put it that way.

>> okay.

>> we need to lower taxes for everyone. everyone. we need to lower those burdens. we need to bring the federal government to the right size to serve us and not to suffocate the economy. we can do it. president obama is a very smart and inspiring leader. we can work together on this. let's not raise taxes on anyone. let's lower those burdens. the president has expressed a desire to consolidate departments of the federal government . let's work on that. we can do that and give dollars back to the american taxpayers who are so hard working and so hard pressed.

Source: http://video.msnbc.msn.com/newsnation/46136034/

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Wednesday, January 25, 2012

McCartney's wife resigns from NYC transit board (omg!)

NEW YORK (AP) ? Paul McCartney's new bride is stepping down from the board of the authority that runs New York City's public transit system.

Nancy Shevell married the Beatles great in October. She announced her resignation from the board of the Metropolitan Transportation Authority at its meeting Wednesday.

Shevell had been on the MTA's board since 2001 and was one of its longest-serving members. Her term expired last year, but she had stayed on pending a new appointment by New York's governor.

When she isn't dating music legends or running subway systems, Shevell is a philanthropist. She was an executive at New England Motor Freight, a New Jersey trucking firm owned by her family.

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_mccartneys_wife_resigns_nyc_transit_board173222951/44302347/*http%3A//omg.yahoo.com/news/mccartneys-wife-resigns-nyc-transit-board-173222951.html

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Mom Is My Wingman

Advances | More Science Cover Image: February 2012 Scientific American MagazineSee Inside

Male monkeys who live at home have more luck with females


Image: Courtesy Carla B. Possamai/Federal University of Espirito Santo

Human males living with their moms may not expect to have much luck hooking up this Valentine?s Day. But among the northern muriqui monkeys, males that spend the most time around their mothers seem to get an added boost when mating time rolls around.

The findings, published in the Proceedings of the National Academy of Sciences USA, suggest that females in some species may have evolved to play a critical role in their sons? reproductive success. Karen Strier, the paper?s lead author and a professor of anthropology at the University of Wisconsin?Madison, says the paper ?extends? the so-called grandmother hypothesis, a concept in which human females evolved to live past their prime reproductive years to spend more time helping offspring.

The research team observed and collected genetic data from a group of 67 wild monkeys living in a protected reserve in Brazil?s Atlantic Forest: infants, mothers and possible sires. They found that six out of the 13 adult males they studied spent more time in close proximity to their mothers than would be expected by chance. These same six monkeys, on average, sired the greatest number of offspring.

The investigators are still trying to figure out why. ?It?s not like we see moms intervening and helping their sons out,? Strier says. ?Maybe by sitting near their moms, they get to see when females are sexually active, or maybe they just get more familiar with other females.? Strier also found that there was no inbreeding among sons and their close female relatives, a process that might also be mediated by mothers. ?Mating may be less random than we think, perhaps because of the influence of the mothers,? she says.

The findings can help with future conservation efforts for the critically endangered species. ?The last thing we would want to do is take a male out of its natal group,? Strier observes.

Source: http://rss.sciam.com/click.phdo?i=1f91fb7af514a69dcf64ce6832c0081b

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Tuesday, January 24, 2012

Summary Box: Stocks waver as Greece talks go on (AP)

EURO UP: The euro rose to a three-week high against the dollar on hopes that the Greek government will reach a deal with creditors to trim the country's debt.

GAS GAIN: Natural gas prices rose after Chesapeake Energy said it will cut production in response to cheap prices and rising supplies. Stocks of gas producers jumped.

STEADY CLIMB: The S&P 500 index edged up 0.62 points Monday to close at 1,316. The stock market is off to a strong start in 2012. Better-than-expected job growth in the U.S. and easing worries about Europe's debt woes have pushed the S&P 500 up 4.6 percent for the year.

Source: http://us.rd.yahoo.com/dailynews/rss/stocks/*http%3A//news.yahoo.com/s/ap/20120123/ap_on_bi_ge/us_wall_street_summary_box

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Women Feel Pain More Intensely Than Men (LiveScience.com)

When a woman falls ill, her pain may be more intense than a man's, a new study suggests.

Across a number of different diseases, including diabetes, arthritis and certain respiratory infections, women in the study reported feeling more pain than men, the researchers said.

The study is one of the largest to examine sex differences in human pain perception. The results are in line with earlier findings, and reveal that sex differences in pain sensitivity may be present in many more diseases than previously thought.

Because pain is subjective, the researchers can't know for sure whether women, in fact, experience more pain than men. A number of factors, including a person's mood and whether they take pain medication, likely influence how much pain they say they're in.

"Whatever the reason, I think it's important to be aware of this pain discrepancy between men and women and look into it further," said study researcher Linda Liu, a doctoral student in Stanford University Biomedical Informatics program.

Future studies, in both people and animals, should analyze their results to see whether sex differences in pain may be present, Liu said. Many studies in animals do not include females, or fail to report the sex of animals used, Liu said.

The study was published online Jan. 12 in the Journal of Pain.

Sex differences

Most human studies examining gender differences in reported pain have compared the number of women with the number of men with a given condition who say they are in pain. But most haven't looked at how intense the pain is, and many have not included enough people to be able to detect differences between the sexes in pain perception, the researchers said.

The new study included information from more than 11,000 patients whose pain scores were recorded in electronic medical records at Stanford Hospital and Clinics between 2007 and 2010. Patients were asked to rate their pain on a scale of zero (no pain) to 10 (worst pain imaginable).

In all, the researchers assessed sex differences in reported pain for more than 250 diseases and conditions.

For almost every diagnosis, women reported higher average pain scores than men. Women's scores were, on average, 20 percent higher than men's scores, according to the study.

Women with lower back pain, and knee and leg strain consistently reported higher scores than men. Women also reported feeling more pain in the neck (for conditions such as torticollis, in which the neck muscles twist or spasm) and sinuses (during sinus infections) than did men, a result not found by previous research.

Pain perception

It could be that women assign different numbers to the level of pain they perceive compared with men, said Roger B. Fillingim, a pain researcher at the University of Florida College of Dentistry, who was not involved with the new study.

But the study was large, and the findings are backed up by previous work, Fillingim said.

"I think the most [simple] explanation is that women are indeed experiencing higher levels of pain than men," Fillingim said.

The reason for this is not known, Fillingim said. Past research suggests a number of factors contribute to perceptions of pain level, including hormones, genetics and psychological factors, which may vary between men and women, Fillingim said. It's also possible the pain systems work differently in men and women, or women experience more severe forms of disease than men, he said.

Future research is needed to find out the exact causes of pain perception differences, and which ones would be best to target for more effective pain control, Fillingim said.

Finding biological markers for pain, such as genes or proteins, would also help take some of the subjectivity out of assessing the experience of pain, Liu said, but the identification of such markers is likely a long way off.

Pass it on: Across many different diseases, women say they experience more pain than men.

This story was provided by MyHealthNewsDaily, a sister site to LiveScience. Follow MyHealthNewsDaily staff writer Rachael Rettner on Twitter @RachaelRettner. Find us on Facebook.

Source: http://us.rd.yahoo.com/dailynews/rss/science/*http%3A//news.yahoo.com/s/livescience/20120123/sc_livescience/womenfeelpainmoreintenselythanmen

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A Century after Scott and Amundsen, the Antarctic Still Beckons

I just started teaching my spring classes, and on the first day a student asked me if my work as a science journalist had taken me to any cool places. I said that in 1985 I rode a trolley into a tunnel at the Nevada Test Site in which a nuclear bomb would be detonated the next day. In 1991 I stood at the edge of an oil field whose wells, ignited by Iraqi troops during the first Gulf War, shot huge jets of fire into the sky, which was so black with smoke that I could barely see my notebook. In 2002 I sat in a teepee on a Navajo reservation eating peyote with 20 members of the Native American Church. But by far the coolest trip I?ve ever taken, I said, took me to the South Pole.

The Antarctic has received lots of press lately. Just over century ago, on January 17, 1912, Robert Falcon Scott arrived at the South Pole, only to discover that Roald Amundsen had arrived there more than a month earlier. Scott and his men perished on their return journey, and ironically their failure is commemorated more than Amundsen?s success.

My expedition?compared to those of these rugged explorers, who relied on dogs, ponies and their own muscles for transport?was like a trip to the mall. Together with three other journalists, I flew in a cavernous C-130 military-transport plane from Christchurch, New Zealand, to McMurdo Station, a gritty American base perched on the edge of Ross Island. From the window of our plane, the Antarctic resembled an endless porcelain landscape, through which jagged black mountains protruded. I felt as though I was visiting not just another part of Earth but another planet.

Just a short tramp from McMurdo was Discovery Hut, built by Scott in 1902 during his first expedition to the Antarctic. The inside of the hut, cluttered with crates and cans of food, was eerily well-preserved, as though Scott and his men might burst through the door at any moment. During my 10-day sojourn (which took place in November, when the sun never sets), my colleagues and I were whisked around on snow cats and a helicopter.

Some other memories from the trip: Peering into the smoking maw of Mt. Erebus, an enormous active volcano. Swooping through a canyon in the Dry Valleys so narrow that I kept thinking the helicopter?s blades were going to strike the rock. Standing on an ice floe as a flock of Emperor penguins leaped out of the sea and waddled toward us, eyeing us with curiosity. Climbing straight down beneath the sea ice into a metal tube, through the windows of which I could see Weddell seals gliding through the frigid twilight.

The high point, however, was when a C-130 flew us from McMurdo to the South Pole?s Amundsen-Scott Station, where some 80 people lived and worked in a geodesic dome and other structures. On that day, the Pole was a balmy 44 degrees Celsius below zero (-47 Fahrenheit), almost 90 below (-130 F) with the wind chill. In the photo that accompanies this column, I?m standing next to the sign that marks the Geographic South Pole.

The Pole was also marked by a column, striped like a candy cane, with a mirrored ball mounted on top. Somewhere in my apartment is a hat, which I bought at Amundsen-Scott, bearing an embroidered likeness of that kitschy column. After our plane touched down, my journalistic colleagues and I watched in astonishment as member of the plane?s crew peeled off his jump suit, stripped down to his underwear and dashed around the column; we learned later that this ritual is required for crew members arriving at the Pole for the first time.

The U.S. National Science Foundation now spends more than $300 million a year to support scientific programs in the Antarctic, about $100 million more than when I visited the continent in 1992. This money is well spent, because it is helping us come to grips with riddles about our past and future. Astrophysicists at the South Pole, which has some of the driest, clearest skies on Earth, have sent balloons aloft to measure the cosmic microwave background, the afterglow of the big bang. The IceCube Neutrino Observatory, just constructed at the Pole, could yield clues about the nature of mysterious ?dark matter? thought to pervade the universe.

Biologists probing frozen Antarctic lakes have discovered new species of bacteria, which may provide clues to the origin of life on Earth more than four billion years ago. Geologists pondering ice cores and rocks have deduced that the Antarctic ice sheet, which to my eyes looked eternal, is anything but. During my visit almost 20 years ago, I learned that the sheet has fluctuated dramatically over the past few million years, and some scientists fear that global warming may shrink the ice enough to trigger a catastrophic surge in sea levels world-wide.

The period during which Scott, Amundsen, Ernest Shackleton and others trekked across the Antarctic has been called the ?Heroic Age of Antarctic Exploration.? We still live in such an age, even if scientists?and journalists?no longer risk their lives in quite the way that those intrepid explorers did.

Source: http://rss.sciam.com/click.phdo?i=63e461c0971f7fb63d05e6f56d518645

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Sunday, January 22, 2012

Duke Upset By Florida State: Michael Snaer Buzzer Beater Halts Blue Devils' Home Win Streak (VIDEO)

DURHAM, N.C. -- For once, Duke wasn't unbeatable in its famed arena.

Michael Snaer hit a 3-pointer at the horn and Florida State beat the fourth-ranked Blue Devils 76-73 on Saturday, snapping Duke's 45-game home winning streak.

The Blue Devils hadn't lost in Cameron Indoor Stadium since falling to rival North Carolina in February 2009. It had been even longer ? five years ? since Duke lost at home to an unranked opponent, though that 64-game streak started after a one-point loss to the Seminoles. The Blue Devils came within a win of matching their own Atlantic Coast Conference record for consecutive home wins before Snaer's final shot.

Of this group, only senior Miles Plumlee was on the team that lost to the Tar Heels here three years ago.

"You just go on," Duke coach Mike Krzyzewski said. "I think Duke fans take it for granted, probably. I'm not knocking them. I just think they take it for granted. It's not unusual for our program. We're very proud of that. We play a high level of teams in here. And to win that much is a testimony to how hard our guys work, every game, every year. ... And there was no pressure. We never talk about that."

The Blue Devils (16-3, 4-1) won 46 straight at home from 1997-2000, and most of the past 45 straight wins had come by double-digit margins. Duke had won 59 of 60 games in Cameron since the start of the 2008-09 season, and is the only ACC program to win at least 40 straight at home ? which the Blue Devils have done three times.

But with Saturday's game tied, Luke Loucks sprinted up the middle of the court before zipping a pass to Snaer on the right side in front of the FSU bench. Snaer quickly launched a shot that dropped through the net at the horn, stunning the once-rowdy Cameron crowd and sending the Seminoles' bench spilling onto the court in celebration.

Snaer scored 14 points ? including a banked-in 3 to beat the buzzer on the final play of the first half ? and the Seminoles (13-6, 4-1) won their fourth straight game.

Austin Rivers had 19 points and tied the game on a driving basket with 4.9 seconds left for the Blue Devils.

Duke led by nine in the first half and by eight midway through the second, but the Seminoles just wouldn't let the Blue Devils pull away. Instead, they kept attacking and knocking down tough shots in one of college basketball's most hostile environments.

In fact, Snaer knocked down a pair of clutch shots in the final minute. On the first, he drove into the paint and knocked down a pull-up for a 71-70 lead with 55.8 seconds left. He followed that with an even bigger one then found himself at the center of a celebration that migrated all the way across the court to stand in front of a stunned group of Cameron Crazies.

Florida State shot 54 percent and knocked down 7 of 14 3-point attempts, following last weekend's 33-point home romp against preseason No. 1 North Carolina with another impressive performance.

Duke overcame its own 40-percent shooting by knocking down 10 3-pointers. The Blue Devils also dominated the offensive boards and outscored Florida State 20-6 on second-chance points, but they just couldn't come up with a final stop to force overtime.

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Source: http://www.huffingtonpost.com/2012/01/22/duke-upset-by-florida-state-snaer-buzzer-streak_n_1221685.html

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No joke: 3-inch nail removed from Ill. man's brain

Dante Autullo accompanied by his neurosurgeon Leslie Schaffer, left, shows the area of his injury during a news conference at Advocate Christ Medical Center Friday, Jan. 20, 2012, in Oak Lawn, Ill., a day after Autullo underwent surgery to remove a 3 1/4 inch nail lodged in his brain after accidentally shooting himself with a nail gun. (AP Photo/M. Spencer Green)

Dante Autullo accompanied by his neurosurgeon Leslie Schaffer, left, shows the area of his injury during a news conference at Advocate Christ Medical Center Friday, Jan. 20, 2012, in Oak Lawn, Ill., a day after Autullo underwent surgery to remove a 3 1/4 inch nail lodged in his brain after accidentally shooting himself with a nail gun. (AP Photo/M. Spencer Green)

This photo provided by Christ Medical Center & Hope Children's Hospital in Oak Lawn,, Ill. on Friday, Jan. 20, 2012 shows an X-ray of a nail embedded in Dante Autullo's brain. Autullo unknowingly shot a nail into his skull, and posted a picture of the X-ray on Facebook during his ambulance ride between hospitals for surgery. (AP Photo/Christ Medical Center & Hope Children's Hospital)

Gail Glaenzer, speaks about her fiance, Dante Autullo's injury in the lobby of Advocate Christ Medical Center Friday, Jan. 20, 2012 in Oak Lawn, Ill., a day after he underwent surgery to remove a 3 1/4 inch nail lodged in his brain after accidentally shooting himself with a nail gun. Autullo is listed in fair condition, and Glaenzer is still trying to process just how lucky the father of her four children was. (AP Photo/M. Spencer Green)

Neurosurgeon Leslie Schaffer, left, smiles as his patient Dante Autullo, shows how he injured himself during a news conference at Advocate Christ Medical Center Friday, Jan. 20, 2012, in Oak Lawn, Ill. The two spoke a day after Autullo underwent surgery to remove a 3 1/4 inch nail lodged in his brain after accidentally shooting himself with a nail gun. (AP Photo/M. Spencer Green)

Neurosurgeon Leslie Schaffer, left, smiles with his patient Dante Autullo, and Dante's fiance, Gail Glaenzer during a news conference at Advocate Christ Medical Center Friday, Jan. 20, 2012, in Oak Lawn, Ill. The trio spoke a day after Autullo underwent surgery to remove a 3 1/4 inch nail lodged in his brain after accidentally shooting himself with a nail gun. (AP Photo/M. Spencer Green)

(AP) ? Dante Autullo was sure he'd merely cut himself with a nail gun while building a shed, and thought doctors were joking when they told him what an X-ray revealed: A 3 1/4-inch nail was lodged in the middle of his brain.

Autullo was recovering Friday after undergoing surgery at Advocate Christ Medical Center in Oak Lawn, where doctors removed the nail that came within millimeters of the part of the brain controlling motor function.

"When they brought in the picture, I said to the doctor 'Is this a joke? Did you get that out of the doctors joke file?'" the 32-year-old recalled. "The doctor said 'No man, that's in your head.'"

As he was rushed by ambulance to another hospital for surgery, he posted a picture of the X-ray on Facebook.

Autullo, who lives in Orland Park, said he was building a shed Tuesday and using the nail gun above his head when he fired it. With nothing to indicate that a nail hadn't simply whizzed by his head, his long-time companion, Gail Glaenzer, cleaned the wound with peroxide.

"It really felt like I got punched on the side of the head," he said, adding that he continued working. "I thought it went past my ear."

While there are pain-sensitive nerves on a person's skull, there aren't any within the brain itself. That's why he would have felt the nail strike the skull, but he wouldn't have felt it penetrate the brain.

Neither he nor Glaenzer thought much about it, and Autullo went on with his day, even plowing a bit of snow. But the next day when he awoke from a nap, feeling nauseated, Glaenzer sensed something was wrong and suggested they go to the hospital.

At first Autullo refused, but he relented after the two picked up their son at school Wednesday evening.

An X-ray was taken a couple hours later. And there, seeming to float in the middle of his head, was a nail.

Doctors told Autullo and Glaenzer that the nail came within millimeters from the part of the brain that controls motor function, and he was rushed by ambulance to the other hospital for more specialized care.

"He feels good. He moved all his limbs, he's talking normal, he remembers everything," Glaenzer said earlier Friday. "It's amazing, a miracle."

Neurosurgeon Leslie Schaffer acknowledged that Autullo's case was unusual, but not extremely rare. Schaffer said having a nail penetrate the skull is not like being shot in the head, noting that a bullet would break into multiple pieces.

"This (the nail) is thinner, with a small trajectory, and pointed at the end," he said. "The bone doesn't fracture much because the nail has a small tip."

Schaffer said the man's skull stopped the nail from going farther into his brain. He said he removed the nail by putting two holes in Autullo's skull, on either side of the nail, then pulled the nail out along with a piece of the skull.

The surgery took two hours, and the part of the skull that was removed for surgery was replaced with a titanium mesh, Hospital spokesman Mike Maggio said.

Glaenzer said Autullo hasn't really talked about how scared he was about what might have happened, but he did express a recognition about coming close to death.

"He was joking with me (after surgery), 'We need to get the Discovery Channel up here to tape this,'" she recalled him saying. "'I'm one of those medical miracles.'"

Associated Press

Source: http://hosted2.ap.org/apdefault/386c25518f464186bf7a2ac026580ce7/Article_2012-01-21-ODD-Nail%20in%20the%20Brain/id-fe2a8bda3c2c4bc5a0e6c1bd2a3918ed

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Saturday, January 21, 2012

Myanmar holds new cease-fire talks with Kachin (AP)

YANGON, Myanmar ? Myanmar's government and ethnic Kachin rebels met Thursday for cease-fire talks to end several months of armed clashes near the northern border with China.

After two days of negotiations, a high-level government team and members of the Kachin Independence Organization agreed to continue talks later and in the meantime to inform the other side before deploying troops, according to an official at the talks who declined to be named.

The talks were the latest efforts by Myanmar's new, nominally civilian government to end the country's long-running ethnic conflicts, one of many reforms under way after years of military rule.

Stopping ethnic clashes is a key demand of Western governments that are weighing lifting sanctions imposed during the junta's rule. Last week, the government signed a cease-fire pact with Karen rebels in eastern Myanmar, in a major step toward ending one of the world's longest-running insurgencies. Other talks are reportedly taking place with the Shan, Karenni and Chin.

A prominent Kachin mediator, Rev. Saboi Jum, told The Associated Press that talks were held across the border in Ruili in China's Yunnan province.

The next round of negotiations would be held in Myanmar, according to the official who spoke anonymously because he was not authorized to disclose details of the talks.

The Kachin Independence Organization reached a peace deal with the country's former ruling junta in 1994, but the truce broke down in 2010 after the group rejected a call by the junta to transform its troops into border guards under the government's leadership.

The Kachin have been fighting the government since June, when the army tried to break up some of their militia strongholds. Thousands of ethnic Kachin have fled their homes to avoid the fighting.

Pro-democracy leader Aung San Suu Kyi has described an end to the fighting with ethnic guerrillas as a national priority, and last month said she would be willing to help with peace negotiations.

The Nobel laureate and former political prisoner sent a letter to the Kachin people expressing compassion, particularly for the women and children who have been uprooted by the fighting, said Saboi Jum.

She "expressed her hope that one day the effected population would be able to come home and live in peace," he said, saying that Suu Kyi's message "lifted our spirits and we are very happy."

Suu Kyi's enormous popularity with the poor and disenfranchised majority is expected to propel her to her first seat in parliament during April by-elections.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120119/ap_on_re_as/as_myanmar_ethnic_rebels

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Should couples share passwords?

Live Poll

Should couples share passwords?

  • 173871

    ABSOLUTELY. Those that have nothing to hide, hide nothing.

    58%

  • 173872

    NO. We're still individuals entitled to privacy and we trust each other.

    42%

VoteTotal Votes: 125

By Athima Chansanchai

Just how much do you trust your spouse or partner? Enough to share passwords? For some, passwords are the final frontier of privacy not only in financial matters, but in social media and email correspondence. But for others, there are no secrets when you're in a relationship?? even risking the potential payback should a break-up sever the happy union.

The New York Times tells us about an "intimate custom" writer Matt Ritchel says is happening between teens in love: "sharing their passwords to email,?Facebook?and other accounts." The desire to be one even extends, the article claims, to couples creating identical passwords and letting each other read private emails and texts.?

For some, it takes a court order to share so much.

But for others, it's imperative to know each other's passwords as part of an open, healthy and fully functioning relationship. Sometimes this comes after a loss of trust, as when one partner has cheated on the other. On the Surviving Infidelity website, where more than 34,000 members have exchanged stories of betrayal and support one another in the forums, there is a saying that becomes a mantra for many of them: "Those who have nothing to hide, hide nothing." To that end, nothing is private anymore in order to facilitate healing for the offended party.?

In this philosophy, those who have been unfaithful should share (or make open and available) not only passwords to their email accounts and Facebook, but also the contents of their text messages, phone logs, work and travel itineraries "without qualms."

Many in those forums mention how finding secret Facebook and email correspondences led to the big reveal of infidelity in their marriages and relationships, and we've seen surveys that attribute at least some fault in Facebook, though an informal poll we took at the end of year showed that nearly half of the 876 votes attributed the demise of their marriages with other factors. But 34 percent did blame Facebook.

Some of the teens in the New York Times article who opened themselves up were dealt a nasty lesson in human nature when their not-so-better halves decided to use the passwords in retaliation for perceived wrongs. The Times listed some examples:

The stories of fallout include a spurned boyfriend in junior high who tries to humiliate his ex-girlfriend by spreading her e-mail secrets; tensions between significant others over scouring each other?s private messages for clues of disloyalty or infidelity; or grabbing a cellphone from a former best friend, unlocking it with a password and sending threatening texts to someone else.

Take our poll and let us know if couples should share passwords.

More stories:

Check out Technolog on?Facebook, and on Twitter, follow?Athima Chansanchai, who is also trying to keep her head above water in the?Google+?stream.

Source: http://digitallife.today.msnbc.msn.com/_news/2012/01/20/10199414-should-couples-share-passwords

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Friday, January 20, 2012

'The Big Bang Theory' 100th Episode: Penny And Leonard 2.0 Software Defined (VIDEO)

In a bold moment that probably surprised him more than the girls, Leonard abruptly walked over to Penny's open apartment door and asked her out on a date. It was the 100th episode of "The Big Bang Theory" (Thu., 8 p.m. EST on CBS), and that apparently meant it was time to re-explore the idea of putting the male and female lead together romantically.

Unfortunately, too much history took the date from awkward to downright unpleasant. Which made the subsequent phone call from Penny in the middle of the night even more unusual. Leonard was accused of thinking too much, so Penny advised him to not overthink this as she led him to their bedroom.

Since they weren't sure what all of this mean, a plan was hatched to explore a sort of new relationship, but in a beta format that only the two of them would know about it. Leonard dubbed it "Penny and Leonard 2.0," and said that to their friends they would just say they'd decided to stay as friends after that bad date.

But Leonard took the pretending too far, and upset Penny again. It's hard to pretend one thing and try to live something else. But then, because this is a show about big brains, viewers got a twist to keep them on their mental toes. It was a risky change of format for the traditional sitcom, but one the cast and creators thought worthy of tackling.

Everything they'd just seen was Leonard overthinking what would happen if he walked over to Penny's open apartment door and asked her out on a date.

He did it anyway, even though it seemed to go badly in every scenario he ran, and events started to play out in a very similar fashion, with a few key changes. Was this now reality, or was this just the beginning of Penny overthinking what would happen if she said yes to Leonoard asking her out on a date -- after a very severe overthink that saw her pregnant at their wedding.

"The Big Bang Theory" gets started on its next 100 episodes every Thursday night at 8 p.m. EST on CBS.

TV Replay scours the vast television landscape to find the most interesting, amusing, and, on a good day, amazing moments, and delivers them right to your browser.

Related on HuffPost:

MONDAY, JANUARY 16: "Alcatraz"

1? of ?20

"Alcatraz" (8 p.m. EST, Fox) two-hour series premiere Produced by J.J. Abrams, this moody mystery series combines procedural elements with a hint of supernatural suspense. Detective Rebecca Madsen (Sarah Jones) and Alcatraz historian Doctor Diego Soto (Jorge Garcia) team up with a secret agency that is dedicated to finding and catching inmates from the infamous prison who went missing 50 years ago and have begun reappearing today. "Alcatraz" (8 p.m. EST, Fox) two-hour series premiere

Produced by J.J. Abrams, this moody mystery series combines procedural elements with a hint of supernatural suspense. Detective Rebecca Madsen (Sarah Jones) and Alcatraz historian Doctor Diego Soto (Jorge Garcia) team up with a secret agency that is dedicated to finding and catching inmates from the infamous prison who went missing 50 years ago and have begun reappearing today.

MORE SLIDESHOWS NEXT?> ??|?? <?PREV

MONDAY, JANUARY 16: "Alcatraz"

"Alcatraz" (8 p.m. EST, Fox) two-hour series premiere Produced by J.J. Abrams, this moody mystery series combines procedural elements with a hint of supernatural suspense. Detective Rebecca Madsen (Sarah Jones) and Alcatraz historian Doctor Diego Soto (Jorge Garcia) team up with a secret agency that is dedicated to finding and catching inmates from the infamous prison who went missing 50 years ago and have begun reappearing today. "; var coords = [-5, -72]; // display fb-bubble FloatingPrompt.embed(this, html, undefined, 'top', {fp_intersects:1, timeout_remove:2000,ignore_arrow: true, width:236, add_xy:coords, class_name: 'clear-overlay'}); });

Source: http://www.huffingtonpost.com/2012/01/20/the-big-bang-theory-100th-episode-penny-leonard-video_n_1218129.html

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